Newbiee HDD question about Iron Wolf and WD Red in same NAS

[jpb]

I have 2 4GB Iron wolf and 2 4GB WD red for a home NAS. Would there be any issues if they are combined in the same VDEV?

 

[c77dk]

I've been using such a combo for a while (6 drives in raidz2) - only downside was the mismatched rpms of the drives, so the REDs kept the pool a little slower. Just need one
Have you made sure the RED are CMR? (now named RED Plus?) otherwise replace them asap. SMR and ZFS equals pain

 

[jpb]

Thanks; these are the WD40EFRX. CMR