I've been using WD Reds -- WD40EFRX and WD60EFRX, and they've been good to me over the past 3 years.
But, my usage is nowhere near intense, and I don't have very many drives in use even over the past 5 years. Over the past 2 years, I had a half dozen 2 GB Seagates fail in succession, so I stay far away from Seagate now.
Backblaze has been tracking lots of stats on their drive reliability in their big data center (~50,000 drives). You can find their latest report here:
https://www.backblaze.com/blog/hard-drive-reliability-q3-2015/
Their data shows the HGSTs are the most reliable, sometimes by a large % over other brands. Followed by WD. They also show a much larger failure rate on Seagates (an order of magnitude higher in some cases, 10% vs 1%), matching my experiences. Interestingly, they use an awful lot of the cheaper NAS class drives, not the enterprise class drives. Also interesting is 4 TB drives show a lesser failure rate than 6 TB drives across multiple brands, even for those where Backblaze has a similar time in service for both.
I'm about to embark on a new FreeNAS build with 16-24 drives, and I'm leaning towards the HGST Deskstar NAS 4 TB. They seem to have a decent price/capacity point (the WD Reds are a bit less expensive), and if the Backblaze data holds they might be a good price/reliability point as well. If I want more capacity for the number of drives, I might try the 6 TB HGST Deskstar NAS. The HGST 8 TB helium & 10 TB SMR drives seem too cutting edge for me right now, and are pretty expensive.