I would do RAIDZ3. And if you didn't need all the space, RAIDZ3 with a hot spare.
Mirrors are nice, but it's sounds like you don't need that performance, and the risk of 2 drives in a single mirror crapping out at the same time are greater than any 3 in your pool. If you do Mirrors, make sure you have backups. (Or do 3 way mirrors, but then you'd only have 4 drives of usable space).