This is purely for personal use and mainly for media storage but I just wanted to move the hard drive I use for backup outside my primary desktop.
I think I'll go with the z3 since that'll give me the most reliability and I'll still have more than enough space left over.
I use offsite backup for smaller data that's more important to me.
I agree with
@Anthony Chastain on one pool... There is a handy space calculator here that will show you the impact of your choices:
https://jsfiddle.net/Biduleohm/paq5u7z5/1/embedded/result/
Have you bought your drives yet? If not, make sure you get drives from different batches (different manufacture dates), and burn them in well. (There are resources on this board-just search).
Those drives are pretty small, and should re-silver fairly quickly in the event of a failure. Unless your stuff is REALLY critical or you get into really big drives, I would think RAID-Z2 should be quite safe. I'm running 8x6TB on RAID-Z2.
If you haven't chosen a case yet, you might want to get one that will give you an open 5-1/4 Inch drive bay. If you have a spare SATA port, you can then create a hot swap backup. I bought some removable cartridges from Addonics, and they have been doing a very nice job. I can push 8TB out to a large single drive pool overnight for an offsite backup. You wouldn't need such a big drive because your main pool is much smaller.
I don't know what your Internet upload speed is like, but unless you have a very fast service it is going to take a very long time to push 1TB up to AWS. Then if you do need to recover, how long is it going to take to get your data back?
Just some thoughts to consider... your needs / budget will dictate your decisions.
Good luck.