The dedicated port can presumably be configured as a separate item. This is not exactly unusual, but the choice to default to one of the system ports violates POLA.
It was moderately loud when I first turned it on for a few seconds, then the fans revved down. But quite frankly the shop is not a quiet environment so that's a total crap assessment.
Also worth noting I do very little work from the shop. I much prefer sitting on my arse in my office or from remote. Unfortunately I am in the process of deploying new Win8.1 based laptops, and part of the process is that installs need to be scriptable (==reproducible). So I am also very busy with a client these past few months, and the new deployment is going extra glacially slow. No Java yet. So I have to wait until I'm back in the office on a more mature OS. And then I can hopefully make some useful assessments.
It would be tricky, not impossible, but tricky to swap a drive. You would need a railset capable of 110% extension. It is unusual but by no means unheard-of for servers to have such rails. In the old days, we'd just go to Accuride and select a suitable set of slides. These days, with the servers typically being a bit wider, it has often been necessary to rely on manufacturer-provided slides in order to obtain something sufficiently narrow that is also no more than 1.75" (1U) tall. The 4-drive 1U storage servers are usually the worst in this regard. Because rail sets that extend 110% are typically track-in-track, and since this thing is 32" deep, I am ... well, skeptical that this has been addressed by ASRock. All I can say for sure is that they didn't include rails and I haven't inquired.
If the top lid were cut, maybe two or three inches in front of the fan bulkhead, it would probably be more feasible to have a set of standard slides and then be able to remove the front lid. However, this might compromise the chassis rigidity. I suspect that the reason for the rear screws is to strengthen and add rigidity.