I wouldn't expect to find server grade system for the ISS or spacecrafts and satellites going into space. Definitely server grade is not going to perform any better than desktop computers. You will need harden hardware for that.
Actually, you'd be pretty amazed at the stuff that goes in space. It always, always, always has ECC (or some other correction type) because of radiation in space. It's almost always custom built for a specific purpose, making it outrageously expensive. A few (mostly cheaper one-time short-lived) satellites use hardware like Supermicro and encase it in shielding with a custom BIOS that does things like crazy memory scrubbing, low power options that are a bit more aggressive, etc. Generally, they take a generic design for what you and I call " server-grade" motherboard (or whatever part you are talking about) and they have the manufacturer setup custom firmware that forces certain settings, disables other ones, etc. What's funny is that they are *way* behind the times when it comes to using the latest tech. In fact, one of the biggest problems for space has been that transistor size has shrunk (duh) which means that a single radiation event causes a significant percentage of a transistor to be ionized (sometimes resulting in a "fire" of a transistor that is supposed to be off). This literally translates into newer CPUs (with smaller transistors) to have much higher error rates than older (and obviously slower) CPUs and in some cases are not reliable enough to even be used. So how do you counter it? Add more shielding. Oh, but shielding adds weight which quickly adds cost to the satellite to get into space. So you have this very delicate balance of CPU processing power and shielding to figure out how to make everything work. Not everyone can take something with the equivalent processing power of an E3-1230v3 and throw it into space while avoiding a pricetag that could exceed the GDP of some countries. ;)
I remember reading a few years ago that Intel had finally pulled the plug on manufacturing the 486 and Pentium lines for hostile environments (they had a specific name for it, but I forget what the word was) like space and such. These weren't your typical 486 and Pentiums though. I want to say this was 2011 or so when I read about it. So just imagine the fact that satellites of 2011 were still being made with those and think about that! LOL
One of the problem with technology in space is that as technology here on earth has progressed it has really hurt the space tech industry because they can't grab off the shelf parts like they did in 1990 and then use them as test platforms. You're doing more and more all-custom designs and demanding transistors of a size from a decade ago so you can minimize shielding for cost reasons.
If you ever get a chance to talk to a NASA engineer that has had to design some of that or got a tour of the stuff the public doesn't get to see, definitely do! I had a rare opportunity due to my military experience and it was something I will never forget.