Here it is, September 10, about 7 weeks after I first read your "@cyberjock's" slideshow. While I didn't take your advice verbatim, I doubled the size of my NAS taking into account your reasoning.
To rehash, so one doesn't have to go back to the original posting, I'd bought an HP Proliant N40L, put 5 2TB disks in at as well as 8GB of RAM, applied the Boot firmware upgrade, and ran FreeNAS 8.2.0 on a ZFS raidz1 (one degree of freedom). The files on the NAS (half of which in the neighborhood of 700MB apiece are write once and read multiple times). This was a Home Office NAS which serves about 9 media devices (including computers with media software installed), of which, about three devices is the maximum at any one time. I purchased one 2TB spare which is still in its packaging for a quick repair if I should get indication of a failure. In addition, I've been backing up all my files offline twice to 500GB internal hard drives using a USB to SATA connection tethered to my Linux running Desktop. At the time I started, 500GB drives were at the "sweet spot" of $/MB. Right now 1TB drives are a better buy, buy considering the time it takes to read/write 500MB, I'll probably continue to buy 500MB drives for backups. Needless to say, I've also put together a database to keep track of my assets.
The 10TB of hard drives yielded about 7.8TB of storage. At the time I started looking at expansion, FreeNAS was reporting about 4.8TB in use. Using the 80% rule I saw that I should begin looking at expansion.
At the time I first built my NAS I did a lot of reading about the 2TB hole and Linux RAID, the issues with Linux licensing of ZFS, the fuse built ZFS module and comparing them with the pluses and minuses if ZFS. I eventually chose ZFS and FreeNAS and am still glad I did, even though, since then one can now compile a ZFS kernel mod for Linux (you just won't find it ---yet--- as a prebuilt binary because of the licensing issue. About the 2TB "hole," at the time of my reading, ZFS was touted as not having that "problem", but this was just at the time 3TB disks were being sold by Seagate and there was more interest in handling drives greater than 2TB in size: GPT and MFT issues, etc. What I did take note of was working with drives greater than 2TB is an issue really worth paying attention to. I was alerted by the manufacturer's failure rate of 10 to the 14th power. The technology of hard disk drives up to 2TB had been in existence long enough by this time for that number to have some real statistics behind it (a Universal Data Set we Statisticians call it).
Keeping all this in mind, I decided to add another vdev (raidz1-1) to my existing pool rather than rebuilding my RAIDZ with 4TB disks. Clearly, the best practice using drives with greater capacity than 2TB would be to create a RAIDZ1 (two degrees of freedom), better yet, a RAIDZ2 (three degrees of freedom); however, even with fiddling around in the Proliant box, the most drives I could put in it would be 5 (which I currently had), and, if I I were to rebuild to a RADIZ1 or RAIDz2, I'd have to come up with some drives I could spool the contents of my RAID off to while I put in the new RAID. All this copying had the potential to put me off line for at least a week (as I have to eat, sleep, and go to work), and I'd end up with some hardware that I'd have to figure out how to "recycle" sometime later.
So... taking the "best" from @cyberdoc's recommendations, I found a SanDigital 5bay tower raid being sold as an "open box." (It looked more like it was a last-on-the-shelf item than an "open box.") for about $150. I bought 5 more 2TB drives from the same manufacturer that built the original drives, so I had similar hardware throughout the RAID. I planned to plug this in the the one last available SATA port on my N40L (the eSATA port). I did NOT need to install the Rocket port multiplier that has bad reviews and came with the SanDigital tower as that was covered by the BIOS mod. I upgraded from the 8GB of Kingston ECC unbuffered RAM aboard to 16GB of the same, rebooted and found the 16GB of RAM was recognized, but I'd lost my original zpool. I found 6 disks were recognized, but I couldn't access the existing zfs pool. Panic!! I spent about 5 hours reading forums and trying a bunch of zfs commands, both on the GUI and via the command line. I imported the volume to find it couldn't be imported as the volume existed, so, after a forum suggestion, I detached the existing volume, rebooted, and imported it again, all to find myself back at "square one."
I was called to dinner (where I had a chance to get "out of the box"). After dinner, I shutdown the N40L, pulled the motherboard out (which, if you read Proliant forums, you learn is not thought of as an easy/fun thing to do, and reseated the SATA cable in the motherboard that goes to the backplane holding the 4-bay RAID array. I'd tried this earlier without pulling out the MB, but it must not have worked. Anyway, after I started up the machine and looked at the number of disks I had, there were 10. This time I imported the volume, then simply extended it using the GUI interface. Extremely easy.
I now have a 14.1TB ZFS with 9.2TB still available (or 14.2TB*0.8-4.9TB=6.5TB). Keeping with @cyberjock's original assertation, the next time I expand (if I'm still alive enough to be doing so,) I'll be looking at big U4 enclosures and whatever best practice with controllers, disk formats, file systems are available - even if it is for a home system. The big increase I saw was a much faster loadup of the file system directory from the remote machines accessing the server; however, and I attribute this to the fact that the new vdev is on a port multiplier, file transfers seem to be a little slower (but still more than adequate for my streaming reads).
I recently saw a 4-bay NAS using 4TB disks at one of the discount houses I buy from priced at about $3500. I've got only about $1700 invested in this setup. I probably use a little more electricity than the 4TB drive setup, but to get RAIDZ2 or RAIDz3, I'd have to buy 2 or 3 more 4TB drives and an enclosure to put them in --- and I'd still back up my files twice offline.