This motherboard severely limits your expansion ability compared to other ATX motherboards. With only one DIMM per channel, you’re limited on memory capacity also. If you really need an ITX board AND you’re willing to sacrifice less SATA ports, only one PCIe slot, half the memory capacity etc etc, then sure go ahead. However, in my opinion, for the extra 3” wide and 5.3”, an ATX board makes a whole lot more sense.